Trigemina, Inc. brings together some of the world’s foremost researchers in brain science.

We use our proprietary targeted Nasal Delivery Technology to deliberately deposit drugs in regions of the central nervous system implicated in the generation of pain, migraine headaches, drug tolerance and a variety of complex CNS disorders. This approach limits side effects, and is expected to yield CNS drugs that patients want to take.

The Promise of Migraine Prevention

Chronic and high frequency episodic migraineurs experience many migraines every month, for many it can be a debilitating disease. The pain is often accompanied with visual disturbances, nausea, vomiting, dizziness, extreme sensitivity to sound, light, touch and smell, and tingling or numbness in the extremities or face.

Trigemina is developing treatments that gradually decrease neural sensitiveness, inflammation and frequency of migraines.

Migraines are a major pubic health issue. Click on the infographic to learn about migraine’s impact in the United States. Similar metrics apply to the rest of the world on a larger scale.”

High Frequency Migraine

High frequency migraine (HFM) refers to the combined conditions of chronic migraine and high frequency episodic migraine. These two debilitating conditions have a staggering impact on the lives of sufferers and their loved ones.

Millions Suffering

3.5% – 4.0% of population has HFM

Chronic Migraine

15+ headaches per month

High Frequency Episodic Migraine

8 to 14 headaches per month